Understanding inherited causes of canine bloat

Gastric dilatation-volvulus (GDV), or bloat, is one of the leading causes of death in dogs, second only to cancer for some breeds, and the number one killer of Great Danes. Despite its prevalence, the cause of bloat is unknown. A multi-disciplinary team is investigating the hormones motilin and ghrelin for the cause of the disease—and better treatments.